San Francisco just got louder in the AI game. Brain Co., founded in 2024 by Jared Kushner of Affinity Partners, Elad Gil of Gil Capital, Luis Videgaray, and Eric Wu of Opendoor, stepped out of stealth with a $30 million Series A. Gil Capital and Affinity Partners led the round, joined by Andrej Karpathy, Aravind Srinivas, Fidji Simo, Patrick Collison, Reid Hoffman, Brian Armstrong, Mark Weinberger, and Andrew Liveris. That roster is not casual capital; it is the kind of syndicate that signals Brain Co. is here to wire enterprise AI into the global system.
This is not another chatbot chasing clicks. Brain Co. built a platform that lets Global 2000 enterprises and governments run generative AI at scale and keep it fresh without endless rebuilds. Every time foundation models advance, Brain Co.’s applications update automatically. No Frankenstein patchwork, no obsolete stack, just AI that stays current. In an industry where tech ages faster than milk, Brain Co. is offering expiration-proof infrastructure.
The numbers already speak. Ten Global 2000 clients, including a strategic tie with OpenAI. Deployments cutting timelines by 80 percent. Costs down 30 percent. Uptime at 99 percent. Over $400 million in value unlocked. Workflows from permits to energy optimization to patient care are not theories; they are live, delivering results in government offices, hospitals, and Fortune 500 boardrooms. When those sectors start bragging about efficiency instead of bleeding cash, you know the platform is landing real punches.
Clemens Mewald runs the show as CEO, bringing product leadership chops from Google Brain, Databricks, and Instabase. He is flanked by founders with reach that spans capital markets, geopolitics, and scaled operations. Add Karpathy, Hoffman, and Armstrong in advisory roles, and Brain Co. has a lineup that looks less like a startup and more like a cabinet meeting crossed with an AI lab. That balance of brains, money, and access is rare, and it is exactly what lets them win enterprise deals before competitors even get a badge at security.
The $30 million fuels an aggressive roadmap: expanding enterprise and government sales, opening EMEA and APAC markets, launching a self-service AI marketplace in Q4 2025, layering in multimodal modules by early 2026, and dropping a low-code builder by the back half of the year. Headcount will double in engineering and customer success by mid-2026. Roles in AI research, DevOps, and solutions architecture are on deck.
The market opportunity is north of $120 billion, and most of the Global 2000 still cannot build this in-house. Brain Co. is positioning itself as the turnkey partner, the one that makes AI adoption less like a gamble and more like a guarantee.

