Affect Therapeutics just locked in $26M in Series B funding led by Allumia Ventures, with continued backing from ARTIS Ventures, City Light Capital, LifeArc Ventures & AlleyCorp. This isn’t just capital, it’s conviction. Affect’s mission is simple but massive: make evidence-based addiction and mental health treatment as easy to access as your favorite app. Fully digital, clinically proven, and designed for the people the system forgot. No travel. No stigma. No waiting. Just care that works.
Founded in 2020 by Kristin Muhlner, Dr. Jeffrey De Flavio & Rachel Lin, Affect was born in AlleyCorp’s venture studio with a sharp purpose, to close the treatment gap for substance use and mental health disorders. Dr. Jeffrey De Flavio, who built Groups Recover Together into the nation’s largest value-based opioid treatment network, saw the blind spot: stimulant addiction. Kristin Muhlner, with deep ops roots at Sprinklr, Framebridge & RollStream, brought the precision. Together, they created a digital clinic that’s not theory, it’s therapy. The only all-virtual treatment program accredited by CARF International. Real science. Real outcomes.
Allumia Ventures, led by Jeff Stolte with Dan Galles & Branden Fini, recognized the scale of what’s unfolding. With exits like Omada Health, Xealth & Press Ganey, they don’t chase hype, they back traction. Add in ARTIS Ventures’ Stuart Peterson, City Light Capital’s Jeff Rinehart, LifeArc Ventures’ Jon Nash & AlleyCorp’s Kevin Ryan, and you’ve got a syndicate built on conviction, not coincidence.
The Affect app feels more like behavioral engineering than telehealth. Gamified therapy, contingency management, CBT & trauma-informed care woven into one seamless platform. Members earn rewards for progress, real incentives backed by NIH & NIDA research. Engagement runs 2–3 times national averages, outcomes double traditional models, and 90% of members pay $0 thanks to coverage from Medicaid, Medicare, UHC, Aetna, Humana, Molina & Centene. Affect isn’t chasing the affluent; it’s empowering the underserved.
With CTO Russell Osborne, CMO Dr. Jon Peeples & CFO David Henderson, Kristin Muhlner is scaling fast, expanding into 20+ states, launching standalone mental health programs for anxiety, depression, bipolar, trauma & OCD. Affect also joined the King County Integrated Care Network, bringing digital treatment to 400K Medicaid enrollees. That’s how transformation happens, quietly, effectively, and nationwide.
This $26M isn’t a headline. It’s a handshake between data & dignity. Affect Therapeutics isn’t asking if virtual recovery works, they’re proving it, one smartphone at a time.

